Legacy BioDesign is proud to announce that “Formulation and Process Development Strategies for Manufacturing Biopharmaceuticals” is now published! We have contributed three chapters (see below) to this volume and hope you will find it helpful in your work. For more information or to purchase a copy, visit www.wiley.com or click on the link below. http://www.wiley.com/WileyCDA/WileyTitle/productCd-0470118121,descCd-tableOfContents.html
The chapters are: "Protein Stability during Bioprocessing"Mark Cornell Manning, Gabriel J. Evans, and Robert W. Payne Legacy BioDesign LLC, Johnstown, CO 80534-6404 USA
Contact us if you have protein stability issues during processing.
"Prediction of Aggregation Propensity from Primary Sequence Information"Mark Cornell Manning, Gabriel J. Evans,Cody M. Van Pelt, and Robert W. Payne Legacy BioDesign LLC, Johnstown, CO 80534-6404 USA
"Chemical Instability of Proteins and Peptides", Elizabeth M. Topp1, Lei Zhang1, Hong Zhao1, Robert W. Payne2, Gabriel J. Evans2, and Mark Cornell Manning2
1Department of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS
2Legacy BioDesign LLC
We have also published the following articles recently:
“Stability of Protein Pharmaceuticals: An Update”, Mark Cornell Manning, Danny K. Chou, Brian M. Murphy, Robert W. Payne, and Derrick S. Katayama, Pharmaceutical Res. 2010, 27: 544-575.
“Ability of Two Natural Products, Nootkatone and Carvacrol, To Suppress Ixodes sculparis and Amblyomma americanum (Acari: Ixodidae) in a Lyme Disease Endemic Area of New Jersey”, Marc C. Dolan, Robert A. Jordan, Terry L. Schulze, Christopher J. Schulze, Mark Cornell Manning, Daniel Ruffolo, Jason P. Schmidt, Joseph Piesman, and Joseph J. Karchesy, J. Econ. Entomol. 2009, 102: 2316-2324.
"Peptide Formulation: Challenges and Strategies", Robert W. Payne and Mark Cornell Manning, Innov. Pharm. Technol. Spring 2009, 28: 64-68.
“Multivariate Analysis of the Sequence Dependence of Asparagine Deamidation Rates in Peptides”, Andrew A. Kosky, Vasumathi Dharmavaram, Gayathri Ratnaswamy, and Mark Cornell Manning, Pharmaceutical Res. 2009, 26: 2417-2428.
"Mixing Properties of Lyophilized Protein Systems: A Spectroscopic and Calorimetric Study", Derrick S. Katayama, John F. Carpenter, Kevin P. Menard, Mark Cornell Manning, and Theodore W. Randolph, J. Pharm. Sci.2009, 98: 2954-2969.
“Impact of Bulking Agents on the Stability of a Lyophilized Monoclonal Antibody”, Jeffrey D. Meyer, Rajiv Nayar, and Mark Cornell Manning, Eur. J. Pharm. Sci.2009, 38: 29-38.
"Stability of Human Serum Albumin during Bioprocessing, Aggregation during Terminal Heat Treatment", Jen-Jen Lin, Jeffery D. Meyer, John F. Carpenter, and Mark Cornell Manning, Intl. J. Biol. Macromol. 2009, 41: 91-96.
“Tools to Enhance Membrane Protein Crystallization”, W. William Wilson, Gregg Whited, Robert W. Payne, Charkes Henry, David H. Johnson, and Larry DeLucas, in: Current Topics in Membranes, 2009,63, 51-178.
